Iván Ortega Blake

Instituto de Ciencias Físicas

Investigador

Biofísica y Ciencia de Materiales



Email:
ivan@fis.unam.mx

Teléfono:
Cuernavaca - (777) 3291-762
CDMX - (55) 5622-7762

Conmutador:
(777) 329-17-77

Red UNAM:
27762

Red UNAM Laboratorio:
27762

Artículos en revistas con arbitraje indizadas (Web of Science, JCR, SCOPUS)

1.- Notable enhancement of Amphotericin B channel activity by applied pressures in the range of MSchannels activation. Liga a la publicación

2.- IN VITRO COMPARATIVE STUDY OF THE ANTITUMORAL EFFECTS OF AMPHOTERICIN B AND ITS DERIVATIVE AMPHOTERICIN A21 IN LUNG CELLS Liga a la publicación

3.- Polyene Antibiotics Physical Chemistry and Their Effect on Lipid Membranes; Impacting Biological Processes and Medical Applications Liga a la publicación

4.- TBC1D10C is a cytoskeletal functional linker that modulates cell spreading and phagocytosis in macrophages Liga a la publicación

5.- Preclinical safety evaluation of amphotericin A21: A novel antifungal Liga a la publicación

6.- Asymmetric bilayers mimicking membrane rafts prepared by lipid exchange: Nanoscale characterization using AFM-Force spectroscopy Liga a la publicación

7.- A general purpose acetonitrile interaction potential to describe its liquid, solid and gas phases Liga a la publicación

8.- Asymmetric bilayers mimicking membrane rafts prepared by lipid exchange: Nanoscale characterization using AFM-Force spectroscopy Liga a la publicación

9.- Biophysical characterization of the insertion of two potent antimicrobial peptides-Pin2 and its variant Pin2 [GVG] in biological model membranes Liga a la publicación

10.- Morphology and dynamics of domains in ergosterol or cholesterol containing membranes Liga a la publicación

11.- A molecular dynamics study proposing the existence of statistical structural heterogeneity due to chain orientation in the POPC-cholesterol bilayer Liga a la publicación

12.- Tetraspanin 33 (TSPAN33) regulates endocytosis and migration of human B lymphocytes by affecting the tension of the plasma membrane Liga a la publicación

13.- Título: Biophysical characterization of the insertion of two potent antimicrobial peptides-Pin2 and its variant Pin2[GVG] in biological model membranes Autores: Brandt Bertrand, Sathishkumar Munusamy, José-FranciscoEspinosa-Romero, Gerardo Corzo, Iván Arenas Sosa, Arturo Galván-Hernández, Iván Ortega-Blake, Pablo Luis Hernández-Adame, JaimeRuiz-García, José-LuisVelasco-Bolom, Ramón Garduño-Juárez, Carlos Munoz-Garay Revista: Biochimica et Biophysica Acta (BBA) - Biomembranes, vol 1862, 183105, 2020. Estatus: PUBLICADO Liga a la publicación

14.- Título: Morphology and dynamics of domains in ergosterol or cholesterol containing membranesAutores: Arturo Galván-Hernández, Naritaka Kobayashi, Jorge Hernández-Cobos, Armando Antillón, Seiichiro Nakabayashi, Iván Ortega-BlakeRevista: Biochimica et Biophysica Acta (BBA) - BiomembranesVolumen: 1862Páginas: 183101Fecha de publicación: 1 Febrero 2020Estatus: PUBLICADO  Liga a la publicación

15.- Título: A Molecular Dynamics Study Proposing the Existence of Statistical Structural Heterogeneity due to Chain Orientation in the POPC-cholesterol bilayer Autores: FernandoFavela-Rosalesa, ArturoGalván-Hernández, JorgeHernández-Cobos, Naritaka Kobayashi, Mauricio D.Carbajal-Tinoco, Seiichiro Nakabayashi, IvánOrtega-Blake Revista: Biophysical Chemistry Volumen: 257 Páginas: 106275, Fecha: Febrero 2020 Estatus: PUBLICADO Liga a la publicación

16.-  José David Flores-Romero, Josué Rodríguez-Lozada, Manuel López-Ortiz, Ricardo Magaña, Iván Ortega-Blake, Ignacio Regla, and Mario Fernández-Zertuche.  Multigram Scale Synthesis of A21, A New Antibiotic Equally Effective and Less Toxic than Amphotericin B. Org. Process Res. Dev. 2016, 20, 1529−1532. Liga a la publicación

17.- Jesús Gonzalo Canché-Tello, Maria Cristina Vargas, Jorge Hernandez-Cobos, Iván Ortega-Blake, Amelier-Lorenzo Solari, Christophe Den Auwer, Jose Mustre de Leon, "Interpretation of X-ray. Absortion Spectra of As(III) in Solution using Monte Carlo simulations". J. Phys. Chem. A.,118(46). 10967- 10973, (2914), DOI : 10.1021/jp5061232  

18.- Rodriguez Plaza JG, Morales-Nava R, Diener C, Schreiber G, Gonzalez Z.D, Lara Ortiz MT, Ortega-Blake I, Pantoja O, Volkmer R, Klipp E, Herrmann A, Del Rio G.,"Cell Penetrating Peptides and Cationic Antibacterial Peptides. Two sides of the same coin". J Biol Chem. May 23;289(21): 14448-57, 2014, DOI: 10.107

19.- Alejandro Ramírez-Solís; Minhhuy Ho; Jorge Hernández-Cobos; Iván Ortega-Blake Theoretical studies on the optimal X(OH)3-H2O (X = N, P, Sb) complexes: Interaction energies and topological analysis of the electronic density. Chem. Phys. Letts., 524,20–24, (2012), doi :10.1016/j.cplett.2011.12.044   Liga a la publicación

20.- Jorge Hernández Cobos, Alejandro Ramirez-Solis, Laurent Maron, and Ivan Ortega-Blake, Theoretical study of the aqueous solvation of HgCl2. Monte Carlo simulations using MP2-derived flexible polarizable interaction potentials.
J. Chem.Phys., 136, 014502 (2012),.[doi:10.1063/1.3673780]  

21.- Swiniarskaa M., Andrzej Leś, Rodeb W., Cieslab J., Millán-Pacheco C, Ortega-Blake I., Pastor N.
Segmental Motions of Rat Thymidylate Synthase Leading to Half-the-Sites Behaviour
Biopolymers 93 549-559 (2010)
 

22.- María Luisa San-Román, Jorge Hernández-Cobos, Humberto Saint-Martin and Iván Ortega-Blake, A theoretical study of the hydration of Rb+ by Monte Carlo simulations with refined ab initio-based model potentials,  Theoret. Chem Acc. 126:197-211, (2010) .
Liga a la publicación

23.- J. Hernández-Cobos,M. Cristina Vargas, A. Ramírez-Solís, and I. Ortega-Blake,  Aqueous solvation of As(OH)3: A Monte Carlo study with flexible polarizable classical interaction potentials, J. Chem. Phys. 133, 114501, (2010)

 

24.- Valdéz-González M.∗ , Saint-Martin, H., Hernández-Cobos, J., Sánchez- Marcos E., Ayala R., Ortega-Blake I.,
"Liquid methanol Monte Carlo simulations with refined potential which includes polarizability, non-additivity and intramolecular relaxation"
Journal of Chemical Physics 127. Art. No. 224507 (2007)
  Liga a la publicación

Artculos en revistas de enseanza indizadas

1.- Los liposomas en nanomedicina: del concepto a sus aplicaciones clnicas y tendencias actuales en investigacin Liga a la publicación

Capítulos de libros

1.- Formation and Nanoscale Characterization of Asymmetric Supported Lipid Bilayers Containing Raft-Like Domains.